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6-Phosphogluconic dehydrogenase from yeast

CAS:

Ref. 3D-JAA07395

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6-Phosphogluconic dehydrogenase from yeast
Biosynth

Product Information

Name:6-Phosphogluconic dehydrogenase from yeast
Brand:Biosynth
Description:6-Phosphogluconic dehydrogenase is an enzyme from yeast, which is a key component of the oxidative phase of the pentose phosphate pathway. It catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate, with the concurrent reduction of NADP+ to NADPH. This enzyme is sourced from yeast, a model organism extensively used in biochemical studies due to its eukaryotic nature and ease of genetic manipulation. The mode of action involves the enzymatic conversion that not only contributes to cellular redox balance by generating NADPH, but also links glycolytic carbohydrate metabolism to biosynthetic processes and antioxidative defense mechanisms. Understanding and investigating this enzyme is critical for studies on metabolic pathways and regulation. Applications of 6-Phosphogluconic dehydrogenase extend to metabolic engineering, where it is employed to enhance NADPH availability for synthetic biology applications. It also serves as a model for studying enzyme kinetics and regulation, providing insights useful for biotechnological advancements and therapeutic research, particularly in areas involving oxidative stress and metabolic disorders.
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Chemical properties

Purity:Min. 95%

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