Product Information
Name:t-Butyl 2-iodobenzoate
Brand:Biosynth
Description:t-Butyl 2-iodobenzoate is a reagent that can be used to access cyclopentenes. The reaction begins with the lithiation of an alkoxycarbonyl group and the subsequent attachment of an electrophilic cyclopentene. The reaction is completed by adding a tertiary amine, which causes carbopalladation of the alkyl lithium intermediate, forming a new carbon-carbon bond. Cyclopentenes can also be accessed by intramolecular reactions using a palladium catalyst and alkoxycarbonyl groups as substrates. Camptothecin moieties are often functionalized with t-butyl 2-iodobenzoate in order to access camptothecin analogs.
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Chemical properties
Molecular weight:304.12 g/mol
Formula:C11H13IO2
Purity:Min. 95%
Technical inquiry about: t-Butyl 2-iodobenzoate
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