8-Bromoadenosine 3',5'-cyclic monophosphate
CAS:
Ref. 3D-NB07972
1g
1,760.00€
2g
3,221.00€
100mg
460.00€
250mg
730.00€
500mg
1,094.00€
Product Information
Name:8-Bromoadenosine 3',5'-cyclic monophosphate
Synonyms:
- 8-Bromo-D-adenosine 3',5'-cyclic monophosphate
Brand:Biosynth
Description:8-Bromoadenosine 3',5'-cyclic monophosphate (8-Br-cAMP) is a cyclic nucleotide that is involved in the regulation of energy metabolism. It is a pharmacological agent that regulates the intracellular levels of cAMP and plays an important role in regulating cell proliferation, differentiation, and survival. 8-Br-cAMP binds to specific protein kinases and alters their activity. It also inhibits the enzymatic activity of DNA polymerase II. 8-Br-cAMP has been shown to inhibit tumor growth in mice with bone cancer. The mechanism by which this drug exerts its antitumor effect appears to be related to increased expression of basic proteins and decreased expression of phosphatase 2A, leading to increased activation of protein kinase A. 8-Br-cAMP also causes cellular accumulation of Ca2+ ions by stimulating an increase in the activity of phospholipase C, which hydrolyzes phosphat
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Chemical properties
Molecular weight:408.11 g/mol
Formula:C10H11BrN5O6P
Purity:Min. 98 Area-%
Color/Form:Beige Powder
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