2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-methyluridine
Ref. 3D-NB167498
500mg
315.00€
Product Information
Name:2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-methyluridine
Brand:Biosynth
Description:2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-methyluridine is a novel nucleoside that is activated with anhydrous ammonia and then converted to the corresponding 5'-O-DMT derivative. The 2'-O-tert-butyldimethylsilyl group protects the 5'-position of the sugar moiety from attack by phosphodiesterases, allowing for its use as a substrate in DNA synthesis. The ribose moiety is also modified at the 2' position, which prevents the formation of 3',5'-cyclic monophosphate (cMP) during dephosphorylation and thereby inhibits viral replication. This nucleotide analog has been shown to be active against HIV, hepatitis B virus, and influenza A virus.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Purity:Min. 95%
Technical inquiry about: 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-methyluridine
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