2'-Deoxy-L-adenosine
CAS:
Ref. 3D-ND04246
1g
390.00€
2g
645.00€
5g
1,227.00€
10g
2,182.00€
500mg
236.00€
Product Information
Name:2'-Deoxy-L-adenosine
Synonyms:
- 9-(2-Deoxy-b-L-erythro-pentofuranosyl)adenine
Brand:Biosynth
Description:2'-Deoxy-L-adenosine is an adenosine analogue that has been shown to inhibit the growth of tumor cells in mice. The mechanism of this inhibition is not well understood, but it is thought that 2'-deoxy-L-adenosine inhibits the adenosine A3 receptor and blocks the activation of toll-like receptors. This drug also has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. It has been used as a model system for studying cellular responses to DNA damage caused by ultraviolet radiation. 2'-Deoxy-L-adenosine also has been shown to have a cytotoxic effect on human HL60 cells, which is mediated by nuclear DNA fragmentation.
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Chemical properties
Molecular weight:251.25 g/mol
Formula:C10H13N5O3
Purity:Min. 98 Area-%
Color/Form:Off-White Powder
InChI:InChI=1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7-/m1/s1
InChI key:InChIKey=OLXZPDWKRNYJJZ-DSYKOEDSSA-N
SMILES:Nc1ncnc2c1ncn2[C@H]1C[C@@H](O)[C@H](CO)O1
Technical inquiry about: 2'-Deoxy-L-adenosine
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