2',3'-Dehydro-5'-O-tritylthymidine
CAS:
Ref. 3D-ND04743
25mg
183.00€
50mg
275.00€
100mg
434.00€
250mg
714.00€
500mg
1,019.00€
Product Information
Name:2',3'-Dehydro-5'-O-tritylthymidine
Synonyms:
- 5-Methyl-1-(5-tritylmethyl-2,5-dihydro-furan-2-yl)-1H-pyrimidine-2,4-dione2',3'-Dehydro-5'-O-trityl-D-thymidine
Brand:Biosynth
Description:2',3'-Dehydro-5'-O-tritylthymidine is an anticancer compound, which is a novel nucleoside phosphoramidite. It is synthesized from thymidine in two steps: first, the 2',3'-dideoxyribose phosphate moiety is prepared by reacting 2',3'-dideoxyribose with chloroacetic acid in the presence of triethylamine, followed by reaction with trityl chloride to form the 5' position of the thymidine. 2',3'-Dehydro-5'-O-tritylthymidine has been shown to inhibit DNA synthesis and antiviral activity.
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Chemical properties
Molecular weight:466.54 g/mol
Formula:C29H26N2O4
Purity:Min. 95%
InChI:InChI=1S/C29H26N2O4/c1-21-19-31(28(33)30-27(21)32)26-18-17-25(35-26)20-34-29(22-11-5-2-6-12-22,23-13-7-3-8-14-23)24-15-9-4-10-16-24/h2-19,25-26H,20H2,1H3,(H,30,32,33)
InChI key:InChIKey=MIAKIEAKHPFXJJ-UHFFFAOYSA-N
SMILES:Cc1cn(C2C=CC(COC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c(=O)[nH]c1=O
Technical inquiry about: 2',3'-Dehydro-5'-O-tritylthymidine
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