2'-Deoxyuridine
CAS:
Ref. 3D-ND06282
1kg
4,634.00€
50g
391.00€
100g
601.00€
250g
1,267.00€
500g
2,333.00€
Product Information
Name:2'-Deoxyuridine
Synonyms:
- 2'-Deoxy-D-uridine
Brand:Biosynth
Description:2'-Deoxyuridine (2'-dU) is an intermediate in the synthesis of thymidylate, which is a precursor for DNA synthesis. It can be prepared through high-performance liquid chromatography. 2'-dU has been shown to inhibit the enzymatic activity of enzymes responsible for synthesizing uridine and thymidylate, leading to neuronal death. 2'-dU has also been shown to have a protective effect against mitochondrial dysfunction induced by hydrogen fluoride. It is also known to bind with toll-like receptor 4 (TLR4), which is involved in inflammatory responses. 2'-dU has been used as a fluorescence probe for nucleic acids and as a polymerase chain reaction (PCR) substrate.
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Chemical properties
Molecular weight:228.21 g/mol
Formula:C9H12N2O5
Purity:Min. 98 Area-%
Color/Form:White Powder
InChI:InChI=1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6-,8-/m1/s1
InChI key:InChIKey=MXHRCPNRJAMMIM-ATRFCDNQSA-N
SMILES:O=c1ccn([C@H]2C[C@@H](O)[C@@H](CO)O2)c(=O)[nH]1
Technical inquiry about: 2'-Deoxyuridine
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