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2'-Deoxy-7-deazaisoguanosine triphosphate

CAS:

Ref. 3D-ND139290

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2'-Deoxy-7-deazaisoguanosine triphosphate
Biosynth

Product Information

Name:2'-Deoxy-7-deazaisoguanosine triphosphate
Synonyms:
  • 4- Amino- 7- [2- deoxy- 5- O- [hydroxy[[hydroxy(ph osphonooxy) phosphinyl] oxy] phosphinyl] - b- D- erythro- pentofuranosyl] - 1
  • 7- dihydro-2H- pyrrolo[2
  • 3- d] pyrimidin- 2- one
Brand:Biosynth
Description:2'-Deoxy-7-deazaisoguanosine triphosphate is a nucleotide analogue that is used as an antiviral agent in the treatment of HIV. It has potent activity against HIV and other retroviruses, including SIV, FIV, and HTLV-1. 2'-Deoxy-7-deazaisoguanosine triphosphate has been shown to act as an activator of DNA polymerase by enhancing the incorporation of deoxynucleotide triphosphates into DNA. It also inhibits the synthesis of viral DNA by inhibiting the activity of reverse transcriptase enzymes. 2'-Deoxy-7-deazaisoguanosine triphosphate can be synthesized from diphosphates and phosphoramidites through a modified phosphoramidite approach that allows for high quality and purity with high yield.
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Chemical properties

Molecular weight:506.19 g/mol
Formula:C11H17N4O13P3
Purity:Min. 95%

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