7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt - 10mM aqueous solution
CAS:
Ref. 3D-ND157324
1mg
1,205.00€
2mg
2,041.00€
5mg
4,637.00€
500µg
735.00€
Product Information
Name:7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt - 10mM aqueous solution
Synonyms:
- 7-Deaza-dGTP.Na
Brand:Biosynth
Description:7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt is a cytosolic small molecule that inhibits the activity of telomerase, an enzyme involved in the replication of chromosomes. It also has inhibitory effects on kinase domains and may be used to treat cancer. 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt binds to human mitochondrial DNA and inhibits gene transcription by hybridizing with it. This results in the inhibition of dopamine production, which can be helpful for treating Parkinson's disease. 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt is structurally similar to 2'-deoxyadenosine 5'-triphosphate (dATP) and can be incorporated into DNA by phosphorylation to form a covalent bond that disrupts the dATP/ATP ratio. This causes cellular energy production to decrease and
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Chemical properties
Molecular weight:506.19 g/mol
Formula:C11H17N4O13P3·xNa
Purity:Min. 95%
Technical inquiry about: 7-Deaza-2'-deoxyguanosine-5'-triphosphate sodium salt - 10mM aqueous solution
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