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2'-Deoxy-5-iodouridine-5'-triphosphate sodium salt - 10mM aqueous solution

CAS:

Ref. 3D-ND31484

1g
2,536.00€
1mg
511.00€
2500µg
865.00€
2'-Deoxy-5-iodouridine-5'-triphosphate sodium salt - 10mM aqueous solution
Biosynth

Product Information

Name:2'-Deoxy-5-iodouridine-5'-triphosphate sodium salt - 10mM aqueous solution
Synonyms:
  • 5I-dUTP
Brand:Biosynth
Description:2'-Deoxy-5-iodouridine-5'-triphosphate sodium salt is a potent inhibitor of thymidylate synthase, an enzyme that catalyzes the conversion of deoxyuridine to thymidylate. 2'-Deoxy-5-iodouridine-5'-triphosphate sodium salt has been found to have a noncompetitive inhibition effect on bacterial DNA replication and is used as a chemotherapeutic agent in the treatment of cancer. It is also used as a radioprotectant during radiation therapy. The optimum concentration for 2'-deoxy-5-iodouridine-5'-triphosphate sodium salt is 10mM, which inhibits bacterial enzymes but does not inhibit mammalian enzymes.
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Chemical properties

Molecular weight:681.97 g/mol
Formula:C9H10N2O14P3I·4Na
Purity:Min. 95%

Technical inquiry about: 2'-Deoxy-5-iodouridine-5'-triphosphate sodium salt - 10mM aqueous solution

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