Product Information
Name:4'-C-Fluoroadenosine 5'-sulfamate
Synonyms:
- Nucleocidin4'-Fluoro-5'-O-sulfamoyladenosine
Brand:Biosynth
Description:4'-C-Fluoroadenosine 5'-sulfamate is a molecule that inhibits protein synthesis by binding to the ribosomes of bacteria. It also has anti-angiogenic effects and can be used as an antimicrobial agent against staphylococci, streptococci, and mycobacteria. 4'-C-Fluoroadenosine 5'-sulfamate has minimal toxicity in humans and is not active against Saccharomyces cerevisiae or Escherichia coli. The optimum concentration for inhibiting protein synthesis in vitro was determined to be between 100 and 500 μM. This compound is inexpensive and can be synthesized from commercially available starting materials. In cell culture assays, this compound showed antimicrobial activity against staphylococci, streptococci, and mycobacteria with MIC values ranging from 0.03 to 1 mM.br>
4'-C-Fluoroadenosine 5'-s
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:364.31 g/mol
Formula:C10H13FN6O6S
Purity:Min. 95%
InChI:InChI=1S/C10H13FN6O6S/c11-10(1-22-24(13,20)21)6(19)5(18)9(23-10)17-3-16-4-7(12)14-2-15-8(4)17/h2-3,5-6,9,18-19H,1H2,(H2,12,14,15)(H2,13,20,21)
InChI key:InChIKey=LTBCQBSAWAZBDF-UHFFFAOYSA-N
SMILES:Nc1ncnc2c1ncn2C1OC(F)(COS(N)(=O)=O)C(O)C1O
Technical inquiry about: 4'-C-Fluoroadenosine 5'-sulfamate
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