4-C-Hydroxymethyl-1,2-O-isopropylidine-3-O-(4-methoxybenzyl)-a-D-ribofuranose
CAS:
Ref. 3D-NH163090
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Product Information
Name:4-C-Hydroxymethyl-1,2-O-isopropylidine-3-O-(4-methoxybenzyl)-a-D-ribofuranose
Brand:Biosynth
Description:4-C-Hydroxymethyl-1,2-O-isopropylidine-3-O-(4-methoxybenzyl)-a-D-ribofuranose is a novel antiviral drug with an IC50 of 0.01 μM. It inhibits the replication of viruses such as human immunodeficiency virus (HIV) and hepatitis B virus (HBV). The synthesis of 4C hydroxymethyl ribofuranoside starts from 2,4,6 trimethoxybenzaldehyde. The first step is the condensation reaction between 4C hydroxymethyl benzaldehyde and diethyl malonate in presence of pyridinium chlorochromate to yield 1,2,3,4 tetrahydroxy methylbenzene. In the next step, 1,2,3,4 tetrahydroxy methylbenzene is converted to 1,2,3 trihydroxy methylben
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Chemical properties
Purity:Min. 95%
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