P3-(1-(2-Nitrophenyl)ethyl) adenosine 5'-triphosphate disodium salt
CAS:
Ref. 3D-NN63886
1mg
355.00€
2mg
569.00€
5mg
1,129.00€
10mg
1,980.00€
25mg
4,537.00€
Product Information
Name:P3-(1-(2-Nitrophenyl)ethyl) adenosine 5'-triphosphate disodium salt
Synonyms:
- Adenosine
- 5'-(tetrahydrogen triphosphate)
- P''-(1-(2-nitrophenyl)ethyl) ester
- disodium saltNPE-caged ATP
Brand:Biosynth
Description:P3-(1-(2-Nitrophenyl)ethyl) adenosine 5'-triphosphate disodium salt (P3-ANP-Na2) is an anticancer drug that belongs to the group of nucleosides. It is a phosphoramidate prodrug that is converted to adenosine 5'-triphosphate (ATP) by intracellular esterases. This prodrug has been shown to inhibit the growth of various types of cancer cells in vitro and in vivo, including leukemia and breast cancer cells. P3-ANP-Na2 binds to DNA by intercalation, inhibiting DNA synthesis and transcription. It also inhibits protein synthesis by inhibiting ribonucleotide reductase and deoxyribonucleotide reductase, which are enzymes responsible for synthesizing DNA precursors from RNA precursors.
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Chemical properties
Molecular weight:700.29 g/mol
Formula:C18H21N6Na2O15P3
Purity:Min. 95%
Color/Form:Powder
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