GM3-Ganglioside labelled by NBD ammonium
Ref. 3D-OG09793
1mg
3,468.00€
100µg
537.00€
200µg
872.00€
500µg
1,917.00€
Product Information
Name:GM3-Ganglioside labelled by NBD ammonium
Synonyms:
- N-Acetyl-a-D-neuraminic acid)-(2->3)-O-b-D-galactopyranosyl-(1->4)-O-b-D-glucopyranosyl-(1->1)-(2S,3R,4E)-2-N-(7-nitrobenz-2-oxa-1,3 -diazol-4-yl)aminooctanamido-4-octadecene-1,3-diol ammonium saltaNeu5Ac(2-3)bDGalp(1-4)bDGlcp(1-1)Cer linked 7-n
Brand:Biosynth
Description:GM3-ganglioside NBD (ammonium salt) has a core disaccharide structure (Galβ1,4Glc) with sialic acid linked α2,3 to the galactose residue with nitrobenzoxadiazole (NBD) linked β to position 1 on the reducing terminal glucose residue, in place of the ceramide fatty acid (Ledeen, 2009). Ganglioside GM3 is strongly associated with human tumors, such as, lung, brain, and melanomas, where it is frequently found to be overexpressed. GM3 ganglioside is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019). GM3 ganglioside is implicated in various other diseases involving chronic inflammation, such as: insulin resistance, leptin resistance, T-cell function, and immune disorders (e.g. allergic asthma). It has also been shown to play an essential role in murine and human auditory systems, and is a common pathological feature of GM3S deficiency is deafness (Inokuchi, 2018).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1,236.36 g/mol
Formula:C55H90N6O24·H3N
Purity:Min. 95%
Color/Form:Powder
Technical inquiry about: GM3-Ganglioside labelled by NBD ammonium
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.