Product Information
Name:H-Ala-Tyr-Pro-Gly-Lys-Phe-NH2
Brand:Biosynth
Description:H-Ala-Tyr-Pro-Gly-Lys-Phe-NH2 is a selective inhibitor of aminopeptidase N. It has been shown to inhibit neutrophil and leukocyte recruitment in rat peritonitis models, as well as to reduce the severity of carrageenan induced paw edema in rats. H-Ala-Tyr-Pro-Gly-Lys-Phe NH2 also inhibits the activation of platelets by aspirin and reduces their aggregation, which may be due to inhibition of PAR4.
PAR4 is a G protein coupled receptor that is activated by proteases such as thrombin and trypsin. Activation of PAR4 induces proinflammatory cytokines, leading to increased leukocyte recruitment and inflammation.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:680.80 g/mol
Formula:C34H48N8O7
Purity:Min. 95%
Technical inquiry about: H-Ala-Tyr-Pro-Gly-Lys-Phe-NH2
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