N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite
CAS:
Ref. 3D-PB08393
2g
227.00€
5g
426.00€
10g
632.00€
25g
1,242.00€
Product Information
Name:N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite
Synonyms:
- 2'-Fluoro-dA CEP2'-Fluoro-Bz-A-CEPN6-Benzoyl-5'-O-DMT-2'-fluoro-2'-deoxyadenosine 3'-CE phosphoramidite
Brand:Biosynth
Description:Nucleoside phosphoramidites are used in the chemical synthesis of oligonucleotides. N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine 3'-CE phosphoramidite, also known as 2'-fluoro-dA CEP, is a modified adenosine with a fluorine atom in the 2’ position to enable the synthesis of non-natural fluorine containing oligonucleotides. Nucleoside phosphoramidites are typically modified by displacement of the diisopropylamine group with the 5’ hydroxyl of the next nucleoside in the presence of an azole catalyst such as 1H-tetrazole or 4,5-dicyanoimidazole. 2'-Fluoro-dA CEP has been used in the synthesis of phosphorothioate oligonucleotides that were highly nuclease resistant yet retained exceptional binding affinity to the RNA targets.
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Chemical properties
Molecular weight:875.95 g/mol
Formula:C47H51FN7O7P
Purity:97%
Color/Form:Powder
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