5'-O-tert-Butyldimethylsilyl-2'-deoxyinosine 3'-CE phosphoramidite
Ref. 3D-PB08888
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Product Information
Name:5'-O-tert-Butyldimethylsilyl-2'-deoxyinosine 3'-CE phosphoramidite
Synonyms:
- 5'-O-tert-Butyldimethylsilyl-2'-deoxy-D-inosine 3'-CE phosphoramidite
Brand:Biosynth
Description:5'-O-tert-Butyldimethylsilyl-2'-deoxyinosine 3'-CE phosphoramidite is a modified nucleotide that can be used as an activator for DNA synthesis. It is also a novel nucleoside with antiviral and anticancer properties. It has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) in human peripheral blood lymphocytes, and it has antiangiogenic activity in vitro. The synthesis of 5'-O-tert-butyldimethylsilyl-2'-deoxyinosine 3'-CE phosphoramidite is accomplished by reacting 2'-deoxyinosine 3'-chloroethylaminophosphonate with tert-butyldimethylchlorosilane followed by treatment with triethylamine. This synthetic intermediate can then be reacted with the desired 5' phosphate group to form the final product.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:566.72 g/mol
Formula:C25H43N6O5PSi
Purity:Min. 95%
Technical inquiry about: 5'-O-tert-Butyldimethylsilyl-2'-deoxyinosine 3'-CE phosphoramidite
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