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N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite

CAS:

Ref. 3D-PB09089

1g
201.00€
2g
358.00€
5g
619.00€
10g
1,026.00€
N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
Biosynth

Product Information

Name:N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
Synonyms:
  • N4-Bz-5'-DMT-5-Me-dC phosphoramiditeN4-Benzoyl-2'-Deoxy-5'-O-DMT-5-methyl-D-cytidine 3'-CE phosphoramiditeN4-Benzoyl-5'-O-DMT-5-me thyl-2'-Deoxycytidine 3'-CE phosphoramidite
Brand:Biosynth
Description:Nucleoside phosphoramidites are widely used as building blocks in the chemical synthesis of oligonucleotides. The use of a chemical synthesis rather than an enzymatic one allows bespoke oligonucleotides of a desired sequence to be obtained. 3’-Cyanoethyl phosphoramidites are typically modified by reaction with the 5’ hydroxyl of the next nucleoside in the desired sequence. The reaction is usually catalysed by 1H-tetrazole or 4,5-dicyanoimidazole in acetonitrile. N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite, also called N4-Bz-5'-DMT-5-Me-dC phosphoramidite, is used in the synthesis of 2’-deoxy-5-methylcytidine-containing oligonucleotides as antisense drugs.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:847.93 g/mol
Formula:C47H54N5O8P
Purity:Min. 95%
Color/Form:White Powder
SMILES:COc1ccc(C(OC[C@H]2O[C@@H](n3cc(C)c(NC(=O)c4ccccc4)nc3=O)C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1

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