N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-CE phosphoramidite
CAS:
Ref. 3D-PB64062
5g
569.00€
10g
839.00€
25g
1,553.00€
Product Information
Name:N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-CE phosphoramidite
Synonyms:
- 5-Me-DMT-2'-O-MOE-C(Bz)-CEP
Brand:Biosynth
Description:Nucleoside phosphoramidites are used in the chemical synthesis of oligonucleotides. Using a chemical approach rather than an enzymatic one allows quick and inexpensive access to custom-made oligonucleotides of the desired sequence. Differently from the enzymatic synthesis, the chemically synthesised oligonucleotide sequence is typically constructed in a 3’ to 5’ direction. N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-CE phosphoramidite, also called 5-Me-DMT-2'-O-MOE-C(Bz)-CEP, has been used in the synthesis of oligonucleotides which are specifically hybridizable with nucleic acids encoding multidrug resistant-associated protein (MRP). The antisense oligonucleotide ISIS 13041 gave almost complete removal of resistance to vincristine, a chemotherapy drug.
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Chemical properties
Molecular weight:922.01 g/mol
Formula:C50H60N5O10P
Purity:Min. 95%
Color/Form:White Powder
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