5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE phosphoramidite
CAS:
Ref. 3D-PD32565
1g
486.00€
2g
837.00€
5g
1,539.00€
10g
1,973.00€
500mg
317.00€
Product Information
Name:5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE phosphoramidite
Synonyms:
- 5'-O-(4,4'-Dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-5-methyluridin-3'-yl]-2-cyanoethyl-N,N'-diisopropylphosphoramidite5'-O-D MT-2'-MOE-thymidine 3'-CE phosphoramiditeDMT-2'-O-MOE-T-CEP5-Me-DMT-2'-O-MOE-U-CE P
Brand:Biosynth
Description:5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE phosphoramidite is a nucleoside phosphoramidite used as a building block for the introduction of uridine units into oligonucleotides. 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE phosphoramidite is used for a broad range of applications including the synthesis of natural and unnatural DNA and RNA strands. Phosphoramidites are the reagent class of choice for oligonucleotide synthesis as they contain readily removable orthogonal protecting groups and can be produced at reasonable scales. The diisopropylamino leaving group is readily cleaved upon exposure to an azole catalyst allowing for a highly efficient coupling reaction with a free hydroxyl group on the growing oligonucleotide and oxidation of the subsequent phosphite triester, followed by beta-elimination of the cyanoethyl group affords the stable phosphodiester linkage.
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Chemical properties
Molecular weight:818.89 g/mol
Formula:C43H55N4O10P
Purity:Min. 95%
Color/Form:White Powder
Technical inquiry about: 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine 3'-CE phosphoramidite
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