Product Information
Name:eIF4A3-IN-2
Brand:Biosynth
Description:eIF4A3-IN-2 is a small molecule inhibitor targeting eIF4A3, which is a DEAD-box RNA helicase. This compound is synthesized from a chemical library designed to modulate RNA-binding proteins. Its mode of action involves binding to eIF4A3 to inhibit its helicase activity, thereby disrupting the process of nonsense-mediated mRNA decay and pre-mRNA splicing. This specific inhibition is particularly valuable for exploring the regulation of gene expression at the post-transcriptional level.
In scientific research, eIF4A3-IN-2 is employed to study the intricate mechanisms of RNA processing and the role of RNA helicases in cellular biology. Its application helps in elucidating the pathways involved in mRNA surveillance and the dynamic regulation of splicing, which can have implications in cancer research and the development of therapeutic strategies targeting dysregulated RNA processing in various diseases. Researchers utilize this inhibitor to better understand the molecular underpinnings of splicing-related pathologies, providing insights into potential interventions for conditions where aberrant RNA metabolism is a hallmark.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:602.7 g/mol
Formula:C25H19Br2ClN4O2
Purity:Min. 95%
Technical inquiry about: eIF4A3-IN-2
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