Product Information
Name:TUG-1375
Brand:Biosynth
Description:TUG-1375 is a highly selective, potent antagonist of the GPR40 (FFAR1) receptor, which is a G-protein-coupled receptor predominantly expressed in pancreatic β-cells. This receptor plays a critical role in mediating free fatty acid-induced insulin secretion. TUG-1375 is sourced from advanced chemical synthesis techniques that ensure both purity and specificity.
The mode of action of TUG-1375 involves its capacity to bind to the GPR40 receptor, thereby inhibiting its activation by endogenous ligands. This blockage impedes the receptor's signal transduction pathways, leading to a decrease in insulin secretion triggered by free fatty acids.
TUG-1375 is extensively utilized in metabolic research, particularly in the study of diabetes and obesity, as it allows for detailed exploration of the GPR40 pathway's role in glucose homeostasis and lipid metabolism. It provides scientists with the capability to manipulate and examine insulin signaling pathways in a controlled environment, advancing the understanding of metabolic disorders and paving the way for potential therapeutic developments.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:442.92 g/mol
Formula:C22H19ClN2O4S
Purity:Min. 95%
Technical inquiry about: TUG-1375
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