Product Information
Name:Biricodar dicitrate (vx-710 dicitrate)
Brand:Biosynth
Description:Biricodar dicitrate (vx-710 dicitrate) is a chemosensitizing agent, which is a synthetic compound designed to modulate drug resistance mechanisms. It is sourced from research efforts aimed at overcoming multidrug resistance in cancer. Biricodar dicitrate acts by inhibiting members of the ATP-binding cassette (ABC) transporter family, particularly P-glycoprotein (P-gp) and multidrug resistance-associated proteins (MRPs). These transporters typically efflux chemotherapeutic agents out of cancer cells, thereby reducing drug accumulation and efficacy.
By blocking these transporters, Biricodar dicitrate allows for increased intracellular concentrations of chemotherapeutic agents, enhancing their cytotoxic effects against resistant cancer cells. This agent is particularly valuable in combination therapies where its role as a resistance modulator can significantly improve the response rate to treatment. Research into its clinical application has focused on various malignancies, highlighting its potential to reverse resistance in otherwise refractory cases and to improve overall treatment outcomes.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:988 g/mol
Formula:C46H57N3O21
Purity:Min. 95%
Technical inquiry about: Biricodar dicitrate (vx-710 dicitrate)
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