Product Information
Name:Ingenol Mebutate
Synonyms:
- 3-Angeloyl Ingenol
- 3-Angelyl Ingenol
- 3-Ingenyl Angelate
- Ingenyl 3-Angelate
- Ingenol 3-Angelate
- PEP005
Brand:Biopurify
Description:Ingenol-3-angelate shows anticancer activity, and P-gp-mediated absorptive transport, dermal penetration, and vascular damage contribute to the anticancer activity of ingenol-3-angelate in vivo; it activates a broad range of PKC isoforms and induces apoptosis in acute myeloid leukemia cells by activating the PKC isoform PKCdelta. Ingenol-3-angelate suppresses HIV infection of primary CD4+ T cells through down-modulation of cell surface expression of HIV co-receptors. Ingenol-3-angelate emerges as a unique local chemotherapeutic immunostimulatory debulking agent that could be used in conjunction with immunotherapies to promote regression of metastases.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:430.541
Formula:C25H34O6
Purity:95%~99%
Technical inquiry about: Ingenol Mebutate
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