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Cernuumolide J

CAS:

Ref. TM-T200239

25mg
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50mg
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100mg
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Cernuumolide J
Targetmol

Product Information

Name:Cernuumolide J
Synonyms:
  • TMJ-105
Brand:Targetmol
Description:Cernuumolide J (TMJ-105) functions as a JAK2/STAT3 inhibitor and exhibits potent activity against HEL leukemia cells by inhibiting their growth in both time-dependent and concentration-dependent manners, with an IC 50 value of 1.79 μM. This compound effectively induces G2/M phase arrest and apoptosis by downregulating the phosphorylation of JAK2, STAT3, and Erk, while simultaneously upregulating the phosphorylation of JNK and p38 MAPK. Cernuumolide J holds potential for research applications in anti-cancer therapy.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:450.52
Formula:C24H34O8
Color/Form:Solid

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