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TOPOI/PARP-1-IN-2

Ref. TM-T200992

10mg
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50mg
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Targetmol

Product Information

Name:TOPOI/PARP-1-IN-2
Brand:Targetmol
Description:TOPOI/PARP-1-IN-2 (compound 6c) serves as a dual inhibitor targeting both PARP-1 and topoisomerase 1 (TOPO-1), with IC50 values of 32.2 nM and 46.2 nM, respectively. This compound exhibits greater selectivity for PARP-1 over PARP-2. Additionally, TOPOI/PARP-1-IN-2 disrupts the S phase of the cell cycle and induces apoptosis in the NCI-60 cancer cell lines.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:358.80
Formula:C16H11ClN4O2S
Color/Form:Solid

Technical inquiry about: TOPOI/PARP-1-IN-2

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