PAK4-IN-5
Ref. TM-T201422
10mg
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50mg
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Product Information
Name:PAK4-IN-5
Brand:Targetmol
Description:PAK4-IN-5 (Compound 12i) is a potent inhibitor of PAK4 (IC50: PAK4 at 7.68 nM, PAK1 at 1872.01 nM) that forms stable interactions with the PAK4 enzyme. This compound effectively inhibits the proliferation and migration potential of MDA-MB-231 cells by hindering the phosphorylation of PAK4 and LIMK1. Additionally, PAK4-IN-5 arrests the cell cycle in the G0/G1 phase, induces apoptosis, and prompts the production of reactive oxygen species. The LD50 in mice is greater than 500 mg/kg (oral).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:522.04
Formula:C31H28ClN5O
Color/Form:Solid
Technical inquiry about: PAK4-IN-5
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