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PD-L1/HDAC-IN-1

CAS:

Ref. TM-T205147

10mg
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50mg
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PD-L1/HDAC-IN-1
Targetmol

Product Information

Name:PD-L1/HDAC-IN-1
Brand:Targetmol
Description:PD-L1/HDAC-IN-1 (Compound 14) is an inhibitor of PD-L1 and HDAC, effectively blocking PD-1/PD-L1 interaction as well as HDAC2 and HDAC3 with IC50 values of 88.10, 27.98, and 14.47 nM, respectively. It exhibits mild cytotoxicity in MCF-7 cells (IC50=19.34 μM) and enhances the expression of PD-L1 and CXCL10, promoting antitumor immune responses by recruiting T cell infiltration into the tumor microenvironment (TME).
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:740.284
Formula:C42H46ClN3O7
Color/Form:Solid

Technical inquiry about: PD-L1/HDAC-IN-1

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