EGFR/COX-2-IN-1
Ref. TM-T205462
10mg
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50mg
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Product Information
Name:EGFR/COX-2-IN-1
Brand:Targetmol
Description:EGFR/COX-2-IN-1 is an EGFR/COX-2 inhibitor that effectively targets EGFRWT, EGFRT790M, COX-1, and COX-2 with IC50 values of 0.12, 0.076, 20.1, and 1.52 μM, respectively. It inhibits MCF-7, HT-29, and A-549 cells with IC50 values of 1.20, 5.14, and 14.81 μM, respectively. The compound induces apoptosis by upregulating Bax protein and downregulating Bcl-2 protein levels. Additionally, EGFR/COX-2-IN-1 significantly increases the proportion of cells in the G2/M phase in MCF-7 cells, demonstrating a broad-spectrum antitumor effect.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:456.52
Formula:C20H17FN6O2S2
Color/Form:Solid
Technical inquiry about: EGFR/COX-2-IN-1
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