BAG3/HSP70-IN-1
Ref. TM-T205498
10mg
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50mg
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Product Information
Name:BAG3/HSP70-IN-1
Brand:Targetmol
Description:USP1-IN-11 (compound 38-P2) is a selective, reversible, and non-competitive inhibitor of USP1 (Ubiquitin-specific protease 1). It activates the DDR (DNA damage repair) pathway, leading to cell cycle arrest and apoptosis, thereby inhibiting cell survival. USP1-IN-11 increases sensitivity to Olaparib in drug-resistant cells and works synergistically with Andrographolide in cancer cells with functional BRCA. In the MDA-MB-436 xenograft model, USP1-IN-11 demonstrates significant dose-dependent antitumor activity.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:537.65
Formula:C28H39N7O4
Color/Form:Solid
Technical inquiry about: BAG3/HSP70-IN-1
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