Product Information
Name:PROTAC CDK9 degrader-11
Brand:Targetmol
Description:PROTAC CDK9 degrader-11 (Compound C3) is an orally active PROTAC CDK9 degrader with a DC50 of 1.09 nM. This compound exhibits cytotoxicity in small cell lung cancer (SCLC) cells, with IC50 values in the nanomolar range. It induces cell cycle arrest at the G0/G1 phase and inhibits cell invasion in DMS114 and DMS53 cells. In addition, PROTAC CDK9 degrader-11 shows antitumor activity in an NCI-H446 xenograft mouse model. (Pink: ligand for target protein CDK9 ligand 3; Black: linker; Blue: ligand for E3 ligase Cereblon E3 ligase Ligand 56)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:807.768
Formula:C39H48Cl2N10O5
Color/Form:Solid
Technical inquiry about: PROTAC CDK9 degrader-11
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