Product Information
Name:FGFR2/3-IN-2
Brand:Targetmol
Description:FGFR2/3-IN-2 (compound 10) is an orally active inhibitor targeting FGFR2 and FGFR3. It exhibits IC50 values of 3.7 nM for FGFR2 and 31.2 nM for FGFR3, with a pre-incubation time of 1 hour. FGFR2/3-IN-2 demonstrates selectivity over FGFR1/4 and other kinases, and does not cause diarrhea or increased serum phosphate in vivo. In the SNU-16 gastric cancer model, FGFR2/3-IN-2 can induce tumor stasis or regression.
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Chemical properties
Molecular weight:522.53
Formula:C29H23FN6O3
Color/Form:Solid
Technical inquiry about: FGFR2/3-IN-2
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