Product Information
Name:N-(4-Aminobenzoyl)-D-glutamic Acid
Controlled Product
Synonyms:
- D-N-(p-Aminobenzoyl)glutamic Acid
Brand:TRC
Description:Applications N-(4-Aminobenzoyl)-D-glutamic acid is an intermediate in the synthesis of R-Methotrexate which is an enantiomer of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.
References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),
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Chemical properties
Molecular weight:266.25
Formula:C12H14N2O5
Color/Form:Neat
InChI:InChI=1S/C12H14N2O5/c13-8-3-1-7(2-4-8)11(17)14-9(12(18)19)5-6-10(15)16/h1-4,9H,5-6,13H2,(H,14,17)(H,15,16)(H,18,19)/t9-/m1/s1
InChI key:InChIKey=GADGMZDHLQLZRI-SECBINFHSA-N
SMILES:Nc1ccc(C(=O)N[C@H](CCC(=O)O)C(=O)O)cc1
Technical inquiry about: N-(4-Aminobenzoyl)-D-glutamic Acid
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