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1-​(4-​Aminophenyl)​-​5,​6-​dihydro-​3-​(4-​morpholinyl)​-​2(1H)​-​pyridinone

CAS:

Ref. TR-A637898

100mg
391.00€
1-​(4-​Aminophenyl)​-​5,​6-​dihydro-​3-​(4-​morpholinyl)​-​2(1H)​-​pyridinone
TRC

Product Information

Name:1-​(4-​Aminophenyl)​-​5,​6-​dihydro-​3-​(4-​morpholinyl)​-​2(1H)​-​pyridinone
Controlled Product
Synonyms:
  • 1-(4-Aminophenyl)-5,6-dihydro-3-(4-morpholinyl)-2(1H)-pyridinone
Brand:TRC
Description:Applications 1-​(4-​Aminophenyl)​-​5,​6-​dihydro-​3-​(4-​morpholinyl)​-​2(1H)​-​pyridinone is an intermediate in the synthesis of Apixaban (A726700), A potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation. References Nevuluri, N. et al.: Monat. fuer Chem., 148, 1477 (2017);
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Chemical properties

Molecular weight:273.33
Formula:C15H19N3O2
Color/Form:Neat
InChI:InChI=1S/C15H19N3O2/c16-12-3-5-13(6-4-12)18-7-1-2-14(15(18)19)17-8-10-20-11-9-17/h2-6H,1,7-11,16H2
InChI key:InChIKey=YUGIGSPFTMLIMA-UHFFFAOYSA-N
SMILES:Nc1ccc(N2CCC=C(N3CCOCC3)C2=O)cc1

Technical inquiry about: 1-​(4-​Aminophenyl)​-​5,​6-​dihydro-​3-​(4-​morpholinyl)​-​2(1H)​-​pyridinone

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