Product Information
Name:5-Bromo-1-(2-fluorophenyl)-2-pentanone
Controlled Product
Synonyms:
- 5-bromo-1-(2-fluorophenyl)pentan-2-one
Brand:TRC
Description:Applications 5-Bromo-1-(2-fluorophenyl)-2-pentanone is an intermediate in the synthesis of Prasugrel (P701150). Prasugrel is a novel antiplatelet agent; it is a third-generation thienopyridine. Antiplatelet agent Prasugrel showed greater platelet inhibition and decreased incidence of ischemic events than Clopidogrel but may induce increased incidence of bleeding in patient with acute coronary syndrome.
References Von Beckerath, N., et al.: Circulation, 112, 2946 (2005), Jernberg, T., et al.: Eur. Heart J., 27, 1166 (2006), Farid, N., et al.: Drug Metab. Dispos., 35, 1096 (2007), Farid, N., et al.: Clin. Pharmacol. Ther., 81, 735 (2007), Jakubowski, J., et al.: J. Cardiovasc. Pharmacol., 49, 167 (2007), Wiviott, S., et al.: N. Engl. J. Med., 357, 2001 (2007),
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Chemical properties
Molecular weight:259.115
Formula:C11H12BrFO
Color/Form:Neat
InChI:InChI=1S/C11H12BrFO/c12-7-3-5-10(14)8-9-4-1-2-6-11(9)13/h1-2,4,6H,3,5,7-8H2
InChI key:InChIKey=JWOWGWXSDRIJDF-UHFFFAOYSA-N
SMILES:O=C(CCCBr)Cc1ccccc1F
Technical inquiry about: 5-Bromo-1-(2-fluorophenyl)-2-pentanone
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