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Chenodeoxycholic Acid-d7 (Major)

CAS:

Ref. TR-C291904

5mg
309.00€
10mg
564.00€
2500µg
177.00€
Chenodeoxycholic Acid-d7 (Major)
TRC

Product Information

Name:Chenodeoxycholic Acid-d7 (Major)
Controlled Product
Synonyms:
  • (3a,5ß,7a)-3,7-Dihydroxycholan-24-oic Acid-d7
  • (+)-Chenodeoxycholic Acid-d7
  • 17ß-(1-Methyl-3-carboxypropyl)etiocholane-3a,7a-diol-d7
  • Chenodeoxycholic Acid-d7
  • Chenodiol-d7
  • CDC-d7
  • Chendol-d7
  • Chenocol-d7
  • Fluibil-d7
Brand:TRC
Description:Applications Chenodeoxycholic Acid-d7 is a labelled analogue of Chenodeoxycholic Acid (C291900), which is a major bile acid in many vertebrates, occurring as the N-glycine and/or N-taurine conjugate. With other bile acids, forms mixed micelles with lecithin in bile which solubilize cholesterol and thus facilitates its excretion. Fcilitates fat absorption in the small intestine by micellar solubilization of fatty acids and monoglycerides. Anticholelithogenic. Epimeric with Ursodiol. In addition, Chenodeoxycholic Acid-d7 is an intermediate in synthesizing Glycochenodeoxycholic Acid-d7 Sodium Salt (G641257), which is a labelled Glycochenodeoxycholic Acid (G641255). A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for References Danzinger, et al.: N. Engl. J. Med., 286, 1 (1972); Iser, J.H., et al.: Drugs, 21, 90 (1981); Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986); Ollila, F., et al.: Langmuir, 17, 7107 (2001); Uekama, K., et al.: Chem. Pharm. Bull., 52, 900 (2004); Tongiani, S., et al.: J. Pharm. Sci., 94, 2380 (2005)
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Chemical properties

Molecular weight:399.62
Formula:C24H33D7O4
Color/Form:Neat
InChI:InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1/i7D2,8D2,12D2,16D
InChI key:InChIKey=RUDATBOHQWOJDD-NWIAMCQOSA-N
SMILES:[2H]C([2H])(C[C@@H](C)[C@H]1CC[C@H]2[C@H]3[C@H](CC[C@@]21C)[C@@]1(C)CC([2H])([2H])[C@@]([2H])(O)C([2H])([2H])[C@H]1C[C@H]3O)C(=O)O

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