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4-Chloro-2-[3-cyclopropyl-1-hydroxy-1-(trifluoromethyl)-2-(propynyl)phenyl]carbamic Acid 4-Chlorobutyl Ester
CAS:
Ref. TR-C365625
50mg
305.00€
500mg
1,909.00€
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Product Information
Name:4-Chloro-2-[3-cyclopropyl-1-hydroxy-1-(trifluoromethyl)-2-(propynyl)phenyl]carbamic Acid 4-Chlorobutyl Ester
Controlled Product
Brand:TRC
Description:Applications 4-Chloro-2-[3-cyclopropyl-1-hydroxy-1-(trifluoromethyl)-2-(propynyl)phenyl]carbamic Acid 4-Chlorobutyl Ester is an impurity in the preparation of Efavirenz (E425000), an HIV-1 reverse transcriptase inhibitor.
References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995); Husain, M. et al.: Ind. J. Chem. Sect. B. Org. Chem. Incl. Medicin. Chem., 48B, 1174 (2009); Pierce, M. et al.: J. Org. Chem., 63, 8536 (1998);
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Chemical properties
Molecular weight:424.25
Formula:C18H18Cl2F3NO3
Color/Form:Neat
SMILES:O=C(Nc1ccc(Cl)cc1C(O)(C#CC1CC1)C(F)(F)F)OCCCCCl
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