N4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine
CAS:
Ref. TR-C542615
10mg
244.00€
50mg
848.00€
100mg
1,500.00€
Product Information
Name:N4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine
Controlled Product
Synonyms:
- 5-Chloro-4-[[4-(diethylamino)-1-methylbutyl]amino]quinoline
Brand:TRC
Description:Applications N4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine is a metabolite of Chloroquine (C379965), a standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labelling of MRP by quinoline-based photoactive drug IAAQ.
References Luthman, H., et al.: Nucleic Acids Res., 11, 1295 (1983), Vezmar, M., et al.: Biochem. Pharmacol., 56, 733 (1998), Krajewski, W.A., et al.: J. Biomol. Struct. Dyn., 16, 1097 (1999),
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Chemical properties
Molecular weight:319.87
Formula:C18H26ClN3
Color/Form:Dark Orange To Dark Brown
InChI:InChI=1S/C18H26ClN3/c1-4-22(5-2)13-7-8-14(3)21-17-11-12-20-16-10-6-9-15(19)18(16)17/h6,9-12,14H,4-5,7-8,13H2,1-3H3,(H,20,21)
InChI key:InChIKey=CHDBGFBFAXJWRC-UHFFFAOYSA-N
SMILES:CCN(CC)CCCC(C)Nc1ccnc2cccc(Cl)c12
Technical inquiry about: N4-(5-Chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine
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