Product Information
Name:(S)-Crizotinib
Controlled Product
Synonyms:
- 3-[(1S)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine
Brand:TRC
Description:Applications (S)-Crizotinib is the S-isomer of Crizotinib (C785000) and a novel potent, selective, and cell permeable MTH1 inhibitor. (S)-Crizotinib can also serve as a promising anticancer agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Huber, K.V.M., et al.: Nature, 508, 222 (2014)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:450.34
Formula:C21H22Cl2FN5O
Color/Form:Off-White To Light Yellow
InChI:InChI=1S/C21H22Cl2FN5O/c1-12(19-15(22)2-3-16(24)20(19)23)30-18-5-4-17(28-21(18)25)13-10-27-29(11-13)14-6-8-26-9-7-14/h2-5,10-12,14,26H,6-9H2,1H3,(H2,25,28)/t12-/m0/s1
InChI key:InChIKey=ZSDTZQWYOPVQMX-LBPRGKRZSA-N
SMILES:C[C@H](Oc1ccc(-c2cnn(C3CCNCC3)c2)nc1N)c1c(Cl)ccc(F)c1Cl
Technical inquiry about: (S)-Crizotinib
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