Product Information
Name:Cucurbitacin B
Controlled Product
Synonyms:
- 19-Norlanosta-5,23-diene-3,11,22-trione
- 25-(acetyloxy)-2,16,20-trihydroxy-9-methyl-
- (2ß,9ß,10a,16a,23E)-
- 19-Nor-9ß,10a-lanosta-5,23-diene-3,11,22-trione
- 2ß,16a,20,25-tetrahydroxy-9-methyl-
- 25-acetate (7CI,8CI)
- (2ß,9ß,10a,16a,23E)-25-(Acetyloxy)-2,16,20-trihydroxy-9-methyl-19-norlanosta-5,23-diene-3,11,22-trione
- Amarine
- Cucurbitacine B
- NSC 144154
- NSC 49451
Brand:TRC
Description:Applications Cucurbitacin B is a tetracyclic triterpenoid, which can induce apoptosis in human hepatoma cells. It can also induce DNA damage and autophagy in MCF-7 breast cancer cells.In the wild, watermelons, cucumbers, and muskmelons produce bitter Cucurbitacins to defend against preditors. Humans have bred these fruits to eliminate these compounds thereby yielding fruits that are more appealing to our palate.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sun, Y., et al.: Eur. J. Pharmacol. 768, 28 (2015); Ren, G., et al.: J. Nat. Med. 69, 522 (2015); C&E News p. 10, Dec. 5, 2016j
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:558.70
Formula:C32H46O8
Color/Form:Neat
InChI:InChI=1S/C32H46O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-13,19-22,25,34-35,39H,11,14-16H2,1-9H3/b13-12+/t19-,20+,21-,22+,25+,29+,30-,31+,32+/m1/s1
InChI key:InChIKey=IXQKXEUSCPEQRD-DKRGWESNSA-N
SMILES:CC(=O)OC(C)(C)/C=C/C(=O)[C@](C)(O)[C@H]1[C@H](O)C[C@@]2(C)[C@@H]3CC=C4[C@@H](C[C@H](O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@]12C
Technical inquiry about: Cucurbitacin B
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