N2'-Deacetyl-N2'-(4-methyl-4-methylthio-1-oxopentyl)maytansine

CAS:
890654-03-2

Ref. TR-D199055

5mg

1,153.00€

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Product Information

Name:N2'-Deacetyl-N2'-(4-methyl-4-methylthio-1-oxopentyl)maytansine

Controlled Product

Synonyms:

N2'-deacetyl-N2'-[4-methyl-4-(methylthio)-1-oxopentyl]-Maytansine

Brand:TRC

Description:Applications N2'-Deacetyl-N2'-(4-methyl-4-methylthio-1-oxopentyl)maytansine is an active metabolite of Maytansine (M197940), inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer. References Remillard, S., et. al.: Science, 189, 1002 (1975); Prota, A.E., et. al.: P. Natl. Acad. Sci. USA, 111, 13817 (2014)

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Chemical properties

Molecular weight:794.39

Formula:C₃₉H₅₆ClN₃O₁₀S

Color/Form:Neat

InChI:InChI=1S/C39H56ClN3O10S/c1-22-13-12-14-29(50-10)39(48)21-28(51-36(47)41-39)23(2)34-38(6,53-34)30(52-35(46)24(3)42(7)31(44)15-16-37(4,5)54-11)20-32(45)43(8)26-18-25(17-22)19-27(49-9)33(26)40/h12-14,18-19,23-24,28-30,34,48H,15-17,20-21H2,1-11H3,(H,41,47)/b14-12+,22-13+/t23-,24+,28+,29-,30+,34+,38+,39+/m1/s1

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