De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride
CAS:
Ref. TR-D215505
50mg
338.00€
500mg
2,182.00€
Product Information
Name:De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride
Controlled Product
Synonyms:
- Cetirizine Dihydrochloride Imp. B (EP)
- Cetirizine Imp. B (EP)
- (RS)-2-[4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl]acetic Acid Dihydrochloride
- Cetirizine Dihydrochloride Imp. B (EP) as Dihydrochloride
- Cetirizine Dihydrochloride Impurity B as Dihydrochloride
- Cetirizine Impurity B as Dihydrochloride
Brand:TRC
Description:Applications De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride, is an impurity of Cetirizine (C281100, 2HCl); a nonsedating type histamine H1-receptor antagonist and a major metabolite of Hydroxyzine (H996500). Pharmacological activity of Cetirizine resides primarily in the (R)-isomer. Also antihystaminic.
References De Vos, C., et al.: Ann. Allergy, 59, 278 (1987); Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987); Fadel, R., et al.: Clin. Allergy, 17, 373 (1987); Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)
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Chemical properties
Molecular weight:417.76
Formula:C19H21ClN2O2•2HCl
Color/Form:White
InChI:InChI=1S/C19H21ClN2O2.2ClH/c20-17-8-6-16(7-9-17)19(15-4-2-1-3-5-15)22-12-10-21(11-13-22)14-18(23)24;;/h1-9,19H,10-14H2,(H,23,24);2*1H
InChI key:InChIKey=NBQBQRKLQXVPIS-UHFFFAOYSA-N
SMILES:O=C(O)CN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1
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