3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib

CAS:
1603814-04-5

Ref. TR-D289540

1g

2,290.00€

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100mg

347.00€

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Salts and Derivatives of Active Pharmaceutical Ingredients (API)

Product Information

Name:3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib

Controlled Product

Synonyms:

4-Quinazolinamine
N-(4-chloro-3-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-
Gefitinib Imp. B (EP)
Gefitinib Impurity B

Brand:TRC

Description:Applications 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib is an impurity of Gefitinib (G304000); a tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR). References Lynch, T.J., et al.: N. Engl. J. Med., 350, 2129 (2004); Engelman, J.A., et al.: Science, 316, 1039 (2007); Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003)

Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:446.90

Formula:C₂₂H₂₄ClFN₄O₃

Color/Form:Neat

InChI:InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-17(23)18(24)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)

InChI key:InChIKey=WTDLLXPLBLPTEP-UHFFFAOYSA-N

SMILES:COc1cc2ncnc(Nc3ccc(Cl)c(F)c3)c2cc1OCCCN1CCOCC1

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