N4-(2,3-Dimethyl-2H-indazol-6-yl)-N4-methyl-2,4-pyrimidinediamine
CAS:
Ref. TR-D447263
10mg
209.00€
25mg
444.00€
100mg
1,540.00€
Product Information
Name:N4-(2,3-Dimethyl-2H-indazol-6-yl)-N4-methyl-2,4-pyrimidinediamine
Controlled Product
Brand:TRC
Description:Applications N4-(2,3-Dimethyl-2H-indazol-6-yl)-N4-methyl-2,4-pyrimidinediamine is a degredation product of Pazopanib (P210925), an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
References Olaussen, K., et al.: Oncogen., 28, 4249 (2009), Sleijfer, S., et al.: J. Clin. Oncol., 27, 3126 (2009), Chan, A., et al.: Drugs, 69, 167 (2009), Patel, P. et al.: J. Mass. Spec., 50, 918 (2015);
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Chemical properties
Molecular weight:268.32
Formula:C14H16N6
Color/Form:Neat
InChI:InChI=1S/C14H16N6/c1-9-11-5-4-10(8-12(11)18-20(9)3)19(2)13-6-7-16-14(15)17-13/h4-8H,1-3H3,(H2,15,16,17)
InChI key:InChIKey=GGALKBHEAIMTPY-UHFFFAOYSA-N
SMILES:Cc1c2ccc(N(C)c3ccnc(N)n3)cc2nn1C
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