Product Information
Name:5-(N,N-Dimethyl)-amiloride-d6 Hydrochloride
Controlled Product
Synonyms:
- 3-Amino-N-(aminoiminomethyl)-6-chloro-5-(dimethylamino)-pyrazinecarboxamide-d6 Monohydrochloride
- N-Amidino-3-amino-6-chloro-5-(dimethylamino)-pyrazinecarboxamide-d6 Monohydrochloride
- (3-Amino-5-dimethylamino-6-chloropyrazinoyl)guanidine-d6 Hydrochloride
Brand:TRC
Description:Applications 5-(N,N-Dimethyl)-amiloride-d6 Hydrochloride is an isotopic analog of 5-(N,N-Dimethyl)-amiloride Hydrochloride (D470570), which has been used to investigate biochemical processes related to the circadian clock in mouse and human cell lines. It can also inhibit sodium-hydrogen exchangers (NHE). NHEs regulate sodium and pH in various tissues.
References Isojima, Y., et al.: Proc. Natl. Acad. Sci. USA 106, 15744 (2009); Masereel, B., et al.: Eur J Med Chem 38, 547 (2003)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:299.09352
Formula:C8H6D6ClN7O•(HCl)
Color/Form:Neat
InChI:InChI=1S/C8H12ClN7O.ClH/c1-16(2)6-4(9)13-3(5(10)14-6)7(17)15-8(11)12;/h1-2H3,(H2,10,14)(H4,11,12,15,17);1H/i1D3,2D3;
InChI key:InChIKey=IIUPTHVVXMBJMQ-TXHXQZCNSA-N
SMILES:Cl.[2H]C([2H])([2H])N(c1nc(N)c(C(=O)NC(=N)N)nc1Cl)C([2H])([2H])[2H]
Technical inquiry about: 5-(N,N-Dimethyl)-amiloride-d6 Hydrochloride
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