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Dimethyl (2-Oxopropyl)phosphonate

CAS:

Ref. TR-D476790

1g
97.00€
5g
163.00€
10g
282.00€
Dimethyl (2-Oxopropyl)phosphonate
TRC

    Product Information

    Name:Dimethyl (2-Oxopropyl)phosphonate
    Controlled Product
    Synonyms:
    • (2-Oxopropyl)phosphonic Acid Dimethyl Ester
    • (Dimethylphosphono)acetone
    Brand:TRC
    Description:Applications Dimethyl (2-Oxopropyl)phosphonate is a common chemical reagent used in the synthesis of pharmaceuticals. Used in the synthesis of phenyl-substituted prostaglandins used as selective antiglaucoma agents. Also used in the synthesis of dipeptidyl enoates as potent rhodesain inhibitors. Rhodesain is the cysteine protease of Trypanosoma brucei parasites which cause African sleeping sickness. References Resul, B. et al.: J. Med. Chem., 36, 243 (1993); Ehmke, V. et al.: ChemMedChem., 8, 965 (2013);
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    Chemical properties

    Molecular weight:166.11
    Formula:C5H11O4P
    Color/Form:Neat
    InChI:InChI=1S/C5H11O4P/c1-5(6)4-10(7,8-2)9-3/h4H2,1-3H3

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