1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE)
CAS:
Ref. TR-D482210
25mg
99.00€
100mg
355.00€
250mg
827.00€
Product Information
Name:1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE)
Controlled Product
Synonyms:
- 9-Octadecenoic acid (9Z)-
- 1,1'-[(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester
- 9-Octadecenoic acid (9Z)-
- (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester (9CI)
- 9-Octadecenoic acid (Z)-
- 1-[[[(2-
Brand:TRC
Description:Applications 1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine (DOPE) is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions. DOPE can be used as an emulsifier to facilitate DNA-liposome complex transport across membranes. It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.
References Misra, S.K., et al.: PLoS One, 8, e68305 (2013); MacDonald, R., et al.: J. Pharm. Sci., 88, 896 (1999); Chen, Y., et al.: Int. J. Nanomedicine, 8, 1573 (2013)
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Chemical properties
Molecular weight:744.034
Formula:C41H78NO8P
Color/Form:Neat
InChI:InChI=1S/C41H78NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39H,3-16,21-38,42H2,1-2H3,(H,45,46)/b19-17-,20-18-/t39-/m1/s1
InChI key:InChIKey=MWRBNPKJOOWZPW-CLFAGFIQSA-N
SMILES:CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COP(=O)(O)OCCN)OC(=O)CCCCCCC/C=C\CCCCCCCC
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