3-Methyl-1-phenyl-2-pyrazolin-5-one(Edaravone)

CAS:
89-25-8

Ref. TR-E335000

1g

237.00€

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Product Information

Name:3-Methyl-1-phenyl-2-pyrazolin-5-one(Edaravone)

Controlled Product

Synonyms:

Phenazone Imp. A (EP)
Antipyrine USP Related Compound A
Antipyrine USP RC A
2-Pyrazolin-5-one
3-methyl-1-phenyl- (8CI)
2,4-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one
1-Phenyl-3-methyl-1H-4,5-dihydropyrazol-5-one
1-Phenyl-3-methyl-2-pyrazolin-5-one
1-Phenyl-3-methyl-5-oxopyrazole
1-Phenyl-3-methyl-5-pyrazolinone
1-Phenyl-3-methyl-5-pyrazolone
3-Methyl-1-phenyl-1H-pyrazol-5(4H)-one
3-Methyl-1-phenyl-1H-pyrazol-5-one
3-Methyl-1-phenyl-2-pyrazolin-5-one
3-Methyl-1-phenyl-2-pyrazoline-5-one
3-Methyl-1-phenyl-4,5-dihydro-1H-pyrazol-5-one
3-Methyl-1-phenyl-4,5-dihydropyrazol-5-one
3-Methyl-1-phenyl-4,5-dihydropyrazole-5-one
3-Methyl-1-phenyl-5-pyrazolone
3-Methyl-1-phenylpyrazol-5(4H)-one
3-Methyl-1-phenylpyrazolin-5-one
4,5-Dihydro-3-methyl-5-oxo-1-phenylpyrazole
5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
5-Methyl-2-phenyl-2H-pyrazol-3(4H)-one
5-Methyl-2-phenylpyrazol-3-one
C.I. Developer 1
Developer Z
Edarabone
Edaravone
Edvaradone
MCI 186
Methylphenylpyrazolone
NCI-C 03952
NSC 12
NSC 26139
NSC 2629
Norantipyrine
Norphenazone
Phenylmethyl pyrazolone
Radicava
Radicut
Antipyrine Related Compound A
See more synonyms

Brand:TRC

Description:Impurity Phenazone EP Impurity A Applications Edaravone inhibits the disease activity in rheumatoid arthritis. Edaravone can significantly enhance IR flap viability and protect flap vessels, which is related to scavenging oxygen free radicals, reducing the consumption of SOD, reducing the extent of lipid peroxidation and inflammation, and protecting functional structure of vessels in the early stages of reperfusion. It also shows protective effects against STZ-induced cognitive impairment, oxidative stress, cholinergic dysfunction and altered protein expressions. Its acts like a free radical scavenger, decreased apoptotic cell death, oxidative damage to DNA and lipids, and angiogenesis through inhibiting JNK and p38 MAPK pathways in AMD, glaucoma, DR, and RVO animal models. References Reeta KH et al. Eur J Neurosci. 2017 Feb 15Masuda T et al. Oxid Med Cell Longev. 2017;2017:9208489Zhang DY et al. J Huazhong Univ Sci Technolog Med Sci. 2017 Feb;37(1):51-56Criswell LA et al. Am J Med. 2002 Apr 15;112(6):465-71.

Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:174.20

Formula:C₁₀H₁₀N₂O

Color/Form:Neat

InChI:InChI=1S/C10H10N2O/c1-8-7-10(13)12(11-8)9-5-3-2-4-6-9/h2-6H,7H2,1H3

InChI key:InChIKey=QELUYTUMUWHWMC-UHFFFAOYSA-N

SMILES:CC1=NN(c2ccccc2)C(=O)C1

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