(7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester
CAS:
Ref. TR-E589325
1mg
318.00€
10mg
2,145.00€
Product Information
Name:(7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester
Synonyms:
- Pregn-4-ene-7,21-dicarboxylic acid
- 11,12-epoxy-17-hydroxy-3-oxo-
- 21,17-lactone
- 7-methyl ester
- (7a,11a,12a,17a)-
- Pregn-4-ene-7,21-dicarboxylic acid
- 11,12-epoxy-17-hydroxy-3-oxo-
- ?-lactone
- methyl ester
- (7a,11a,12a,17a)- (9CI)
- Spiro[11,12-epoxy-17H-cyclopenta[a]phenanthrene-17,2'(3'H)-furan]
- See more synonyms
Brand:TRC
Description:Applications (7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester is an impurity of eplerenone (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),
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Chemical properties
Molecular weight:414.491
Formula:C24H30O6
Color/Form:Neat
InChI:InChI=1S/C24H30O6/c1-22-7-4-13(25)10-12(22)11-14(21(27)28-3)17-15-5-8-24(9-6-16(26)30-24)23(15,2)20-19(29-20)18(17)22/h10,14-15,17-20H,4-9,11H2,1-3H3/t14-,15+,17+,18-,19+,20+,22+,23-,24-/m1/s1
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