- Food Industry Standards
- Inhibitor Enzymes
- Miscellaneous Organic Molecules with Isotopical Substitutions
Product Information
Name:Gleevec-d8 Mesylate (Imatinib-d8 Mesylate)
Controlled Product
Synonyms:
- Benzamide
- 4-[(4-methyl-1-piperazinyl-2,2,3,3,5,5,6,6-d8)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-
- methanesulfonate (1:1)
- 4-[(4-Methyl-1-piperazinyl-2,2,3,3,5,5,6,6-d8)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate
- 4-[(4-Methyl-1-piperazinyl-d8)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate
- 4-(2,2,3,3,5,5,6,6-Octadeuterio-4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]benzamide methanesulfonate
- Genfatinib-d8 mesilate
- Imatinib-d8 mesilate
- Imatinib-d8 mesylate
- Imatinib-d8 methanesulfonate
- Imatinib-D8 (piperazinyl-D8) mesilate
Brand:TRC
Description:Applications A deuterated tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL). It is a COVID19-related research product.
References Schindler, T., et al.: Science, 289, 1938 (2000), Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:597.76
Formula:C292H8H23N7O·CH4O3S
Color/Form:Neat
InChI:InChI=1S/C29H31N7O.CH4O3S/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36;1-5(2,3)4/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34);1H3,(H,2,3,4)/i14D2,15D2,16D2,17D2;
InChI key:InChIKey=YLMAHDNUQAMNNX-NZEOXOADSA-N
SMILES:CS(=O)(=O)O.[2H]C1([2H])N(C)C([2H])([2H])C([2H])([2H])N(Cc2ccc(C(=O)Nc3ccc(C)c(Nc4nccc(-c5cccnc5)n4)c3)cc2)C1([2H])[2H]
Technical inquiry about: Gleevec-d8 Mesylate (Imatinib-d8 Mesylate)
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